Zymeworks

Scientist, In Vivo Biology/Pharmacology

Multispecific Antibody Therapeutics - Vancouver, BC

Why Work for Us?

Innovation. Act with Integrity. Collaboration. Embrace Diversity. Care

We come from many countries, cultures, races, ethnicities, abilities, and nationalities. We bring our passions including singing, biking, swimming, dancing, cooking, volunteering, parenting, coaching and much more! We are proud of our nearly equal balance of men and women and strengthened by our non-binary and transgender team members. Every employee belongs.

We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.

Company Description

Zymeworks is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation bispecific and multifunctional biotherapeutics, initially focused on the treatment of cancer. Zymeworks’ suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly-differentiated product candidates.

Zymeworks is seeking a highly-motivated professional who is looking to grow their career with our company.

This position will report to the and will be based in Vancouver, BC.

As a condition of employment, Zymeworks requires all employees to be fully vaccinated against Covid-19 and provide verification of such.

Key Responsibilities

• Oversees all aspects of designing, planning, coordinating, and analyzing in vivo immuno-oncology efficacy and PK/PD experiments in collaboration with project team members.
• Manages studies with both internal counterparts and external contract research organizations (CROs).
• Evaluates emerging technologies, develops new in vivo models, and establishes standard protocols and best practices.
• Provides leadership, mentorship, and scientific/technical guidance to junior staff.
• Summarizes and presents results to supervisor in a logical manner, verbally and in written reports or presentations. Must present data to project team meetings.
• Analyzes data using software including Excel, GraphPad Prism, FlowJo and authors electronic lab notebook entries suitable for IND enabling documentation.
• Actively works to foster an environment of effective and collaborative working relationships amongst employees, management, and external partners.

Qualifications and Education

• PhD in pharmacology, cancer biology, or a related scientific discipline and a minimum of 3 years related experience or an equivalent combination of education and experience.

Skills and Abilities:

• Expertise in running xenograft, syngeneic, or humanized mouse tumor models (PBMC and/or CD34).
• Understanding how to adapt in vitro findings to in vivo study design and dosing regimens for immune-oncology models.
• Demonstrated understanding of in vivo cancer models, therapeutic mechanisms of actions, relationship of PK to therapeutic activity; demonstrated experience with antibody-based therapeutics is an asset.
• Excellent organizational skills to manage multifaceted studies in a fast-paced environment and meet deadlines within projected budgets.
• Experience working with contract research organizations (CROs) for designing, coordinating, and carrying out large scale in vivo studies and summarizing findings to project teams.
• Proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional scientific projectProficient in animal handling, dosing (SC, IP, IV), collection of blood and tumor samples is beneficial.

How to Apply

NOTE TO EMPLOYMENT AGENCIES: Zymeworks values our relationships with our Recruitment Partners. We will only accept resumes from those partners whom have been contracted by a member of our Human Resources team to collaborate with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract.

Zymeworks

Zymeworks is an Equal Opportunity Employer

Submitted: 04/15/2022